Is it possible to have “two” sets of tags?

I have several Custom Category Taxonomies but what I am wondering is, if it’s possible to have a second set of “tags”?

I am using my tags for a very specific purpose (the naming of cities) so I don’t want to mix up that with what I need for another set of tags.

Sure, I can create another Category Taxonomy but the quantity of items means that a “tag” environment might be better…

Thanks